Custom or standard batch chromatography systems

With YMC you leverage our 40 years supplying separations and purification technologies to leading chromatography system users gaining access to cutting edge downstream process scale systems, columns, resins and services across the globe.  YMC Process Technologies offers both a pre-engineered, configurable platform of advanced EcoPrime LPLC's as well as custom designs engineered in concert with your team. We are open to collaborative design built on our pioneering and proven platform designs. Analytical accuracy at pilot and production scale! 

Accuracy previously only attainable in analytical instruments.  With gradient accuracy well below +/-0.5%, yield and purity are enhanced to levels previously only attainable in analytical instruments. YMC Process Technologies has been making enormous strides in the hardware and now enhances our offering with LPLC columns, methods development and resins from YMC.

  • Learn more: NEW Brochure
  • Learn more: Fun, informative Video
  • Learn more: Brief Video walk through of new 2 in 1 system

Buffer dilution and digital control

With YPT’s exclusive  on-board buffer in-line dilution (BID) option our EcoPrime  LPLC systems reduce clean room space constrictions by performing the work of multiple competitive process units using only a single YPT process unit. With BID built into the system users can save tons of space using concentrates precisely diluted at the point-of-use.

Adding proprietary digital enhancements and piping refinements to our already robust fluid control technology has earned us a reputation for innovation among global leaders in biotechnology. The digitization that allows precise metering of feed and buffers has allowed YPT’s EcoPrime LPLC to enhance yield, quality and reproducibility in chromatography steps that has not previously been available to users.

The choice is yours

We leverage a long history of fluid engineering and intellectual property in the advanced solutions we customize to the needs of our customers. We don’t sacrifice the accuracy at any point in that range while delivering footprint savings.

YMC Process Technologies off-the-shelf products and customized solutions enable you with:

  • Analytical performance at pilot and process scale!
  • Single skid systems that offer the flow range (capacity) of 2 competitive systems
  • Unmatched accuracy and reproducibility
  • Flexibility in your processing/automation control - customer adaptable PLC based software and DeltaV options
  • Unique on-board Buffer In-line Dilution options
  • Reduced footprint by up to 66%
  • NEW - EcoPrime Twin LPLC - twin column pilot for batch or continuous process in GMP environments

We offer systems, resins and columns for a variety of methods including:

  • Affinity Chromatography
  • Ion Exchange Chromatography
  • Mixed / Multimodal Chromatography
  • Hydrophobic Interaction Chromatography
  • Size exclusion, including gel filtration
  • Reversed Phase Chromatography
  • Custom high-performance liquid chromatography (HPLC) systems

NEW! Twin column (2 PCC) continuous LPLC system

Multi-column (continuous batch) chromatography is a reality at YPT. While others are only talking about it, YPT customers have been using this technology to produce GMP clinical material. The Contichrom (formerly known as EcoPrime) TWIN LPLC is so advanced and so simple YMC is leading the innovation trend to continuous production with at-scale systems for the production environment. We scale up on YMC ChromaCon's patented twin column technology.

Download the Contichrom TWIN Fact Sheet here.

Recent News on Contichrom TWIN LPLC: Click here